Graft rejection is caused by A. B-cell response B. T-cell response
Question
Graft rejection is caused by A. B-cell response B. T-cell response
Solution
Graft rejection is primarily caused by a T-cell response. When a new organ is transplanted, the recipient's immune system may recognize it as foreign and mount an immune response against it. This is primarily mediated by T cells, which can directly kill cells of the transplanted organ, or stimulate other parts of the immune system to attack the organ.
Here's a step-by-step breakdown:
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The recipient's immune system recognizes the transplanted organ as foreign. This is because the cells of the transplanted organ have proteins on their surface that are different from those on the recipient's own cells.
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This recognition is primarily done by T cells. T cells have receptors that can bind to these foreign proteins.
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Once the T cells recognize the foreign proteins, they become activated. This means they start to multiply and produce substances that help coordinate an immune response.
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Some of these activated T cells, called cytotoxic T cells, can directly kill cells of the transplanted organ.
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Other T cells, called helper T cells, stimulate other parts of the immune system to attack the transplanted organ. For example, they can stimulate B cells to produce antibodies against the foreign proteins.
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This immune response against the transplanted organ is what we call graft rejection.
So, the answer is B. T-cell response.
Similar Questions
Graft transplantation to save certain patients fails due to the rejection of such organs by the patient. Which type of immune response is responsible for such type of rejection?
Rejection happens when the recipient's immune system attacks the transplanted tissues as it recognises them as foreign invaders.Why is rejection not a concern with transplants from a therapeutic clone?The transplanted cells are sterile because they have come from a lab, this means they would not trigger the immune system of the patient.The transplanted cells are a closer match to the patients own cells, which reduces the likelihood of rejection.The patient has been treated with medication to lower their immune system, this prevents immune rejection of the new cells.The transplanted cells are genetically identical to the patient, so they are the patient's cells and the immune system would not attack them as invaders.
The ability of the immune system to attack transplanted tissue from an unrelated donor is mysterious because T cells should not be able to bind to foreign _______.1 pointMHC I and II moleculesendogenous (cytosolic) antigensexogenous (phagocytized) antigensβ microglobulinslipids and glycolipids
The rejection of a transplanted organ is an example of a(n) _____ conditionGroup of answer choicesB cell–mediatedisoimmuneautoimmuneT cell–mediated
Which cells are the most responsible for the rejection of a transplanted organ, such as a heart?Group of answer choicesmacrophagesB cellseosinophilsT cells
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