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The regulation of Acetyl-CoA Carboxylase 1 is shown below. This is the rate-regulating step in fatty acid synthesis. What happens to the levels of malonyl-CoA if glucagon is present?Group of answer choicesThey would increaseThey would decrease

Question

The regulation of Acetyl-CoA Carboxylase 1 is shown below. This is the rate-regulating step in fatty acid synthesis. What happens to the levels of malonyl-CoA if glucagon is present?Group of answer choicesThey would increaseThey would decrease

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Solution

The levels of malonyl-CoA would decrease. This is because glucagon inhibits Acetyl-CoA Carboxylase 1, the enzyme that converts Acetyl-CoA to malonyl-CoA. Therefore, when glucagon is present, less Acetyl-CoA is converted to malonyl-CoA, leading to a decrease in malonyl-CoA levels.

Similar Questions

What role does malonyl CoA play in fatty acid biosynthesis?A) It inhibits the activity of Acetyl-CoA Carboxylase (ACC).B) It serves as a substrate for Acyl Carrier Protein (ACP).C) It activates fatty acid synthase enzymes.D) It promotes the formation of ketone bodies.

Glucagon causesGroup of answer choicesan increase in fatty acid synthesis and lipid storageAn increase in blood glucose concentrationAn increase in glycogen synthesisAn increase in glucose utilisation and storage

How does glucagon increase blood glucose levels?Group of answer choicesBy activating pyruvate kinaseBy activating glycogen phosphorylaseBy activating glycogen synthaseBy activating PFK-1

Malonyl-CoA is an intermediate in fatty acid synthesis and an inhibitor of long-chain fatty acid transport to the mitochondria.  Given this information, which of the following experimental results would provide evidence that a certain drug causes cells to carry out increased beta oxidation?A.Adding malonyl-CoA to drug-treated cells causes an increase in the level of cytosolic acetyl-CoA compared to cells without malonyl-CoA treatment.B.Adding malonyl-CoA to drug-treated cells causes a decrease in the level of mitochondrial acetyl-CoA compared to cells without malonyl-CoA treatment.C.Treating cells with the drug results in a decreased concentration of cytosolic malonyl-CoA compared to untreated cells.D.Treating cells with the drug results in an increased concentration of cytosolic malonyl-CoA compared to untreated cells.Submit

The pathways of fatty acid synthesis and breakdown are similar in that they bothGroup of answer choicesoccur in the same place in a cellinvolve Acetyl CoAinvolve Malonyl CoAare made of the same steps, just occurring in opposite directionsinvolve NADPH

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