Which of the following drugs inhibits intestinal absorption of cholesterol

Which of the following medications inhibits lipase enzyme action in the small intestine and therefore decreases fat digestion by about 30%?Multiple choice question.OrlistatPhenteramineQsymiaBupripion

Harry has hear about another type of drug termed a bile acid sequestrant can also reduce "blood cholesterol"Please mark True or False in response to the following statementHis doctor has told him that it works by blocking the re-absorption of cholesterol secreted in the bile.Group of answer choicesTrueFalse

A propos des acides biliaires, lesquelles de ces propositions sont justes ?AIls représentent la forme d'élimination du cholestérolBIls permettent l'émulsification des graisses alimentairesCLeur conjugaison avec la taurine et le glycocol favorise leur élimination rénaleDIls activent leur propre synthèse par inhibition de la cholestéral-7a-hydroxylaseEIls subissent une déconjugaison dans la lumière intestinale

AbsorptionDrug moves from site of administration into the blood, crossing at least one membrane (except if administered IV)To cross membranes, drugs must be in solution and lipid solubleInfluenced by..oRoute of administrationoDosage form – solution, tablet, suppository, etc.oSolubility of the drug – if lipid soluble, drugs cross membranes more easilyoOther factors – food in stomach, type of food in stomach; movement of drug through stomach and small intestine, pH of stomach/intestinal fluids, etc.First-pass effect – influences bioavailability of the drugBioavailability of the drug - “portion of a [drug] dose that reaches systemic circulation and is available to act on body cells

Synthesis of cholesterol takes place in theGroup of answer choicespancreasgall bladderliversmall intestine