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Sodium chloride contained in glomerular filtrate is not fully reabsorbed in renal tubule.

Question

Sodium chloride contained in glomerular filtrate is not fully reabsorbed in renal tubule.

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Solution

The statement is not entirely correct. Sodium chloride (NaCl) in the glomerular filtrate is indeed reabsorbed in the renal tubules, but not fully. The process of reabsorption of sodium (Na+) and chloride (Cl-) ions occurs primarily in the proximal convoluted tubule and the Loop of Henle in the nephron of the kidney.

  1. In the proximal convoluted tubule, about 65% of NaCl is reabsorbed into the bloodstream. This process is largely driven by the active transport of Na+ ions, with Cl- ions and water following passively due to electrochemical and osmotic gradients.

  2. In the descending limb of the Loop of Henle, water is reabsorbed but NaCl is not, which concentrates the filtrate.

  3. In the thick ascending limb of the Loop of Henle, NaCl is actively reabsorbed but water is not, which dilutes the filtrate. By the time the filtrate leaves the Loop of Henle, about 85% of the NaCl has been reabsorbed.

  4. Further reabsorption of NaCl occurs in the distal convoluted tubule and the collecting duct, regulated by hormones such as aldosterone and antidiuretic hormone (ADH).

However, a small amount of NaCl remains in the filtrate and is excreted in the urine. This is necessary to maintain the balance of electrolytes in the body. The kidneys adjust the amount of NaCl reabsorbed according to the body's needs. If the body has too much NaCl, less is reabsorbed and more is excreted in the urine. If the body needs more NaCl, more is reabsorbed and less is excreted.

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