PFT test findings moderate to severe CF  lung pathophysiology may include the following:1. Decreased FVC2, Decreased FEV1/FVC ratio3. Increased RV4. Increased PEFR

The Pulmonary Function Test (PFT) is a diagnostic tool used to evaluate the function of the lungs. In the context of moderate to severe Cystic Fibrosis (CF) lung pathophysiology, the PFT test findings may include:

1. Decreased Forced Vital Capacity (FVC): FVC is the total amount of air a person can exhale forcefully after taking the deepest breath possible. In CF, this value may be decreased due to the buildup of thick, sticky mucus in the lungs that obstructs airways and reduces lung capacity.

2. Decreased FEV1/FVC ratio: FEV1 (Forced Expiratory Volume in 1 second) is the amount of air a person can forcefully exhale in one second. The FEV1/FVC ratio is used to assess the presence and severity of obstructive lung diseases. In CF, this ratio may be decreased due to obstruction of the airways.

3. Increased Residual Volume (RV): RV is the amount of air left in the lungs after a maximal exhalation. In CF, this value may be increased due to air trapping caused by the obstruction of the airways.

4. Increased Peak Expiratory Flow Rate (PEFR): PEFR is the maximum flow rate generated during a forceful exhale, starting from full lung inflation. In CF, this value may be increased in early stages due to the body's attempt to compensate for the obstructed airways. However, as the disease progresses, PEFR may decrease due to worsening lung function.