Multi-layer drug in adhesive TDDS consists of : Question 16AnswerBacking ⇒ Reservoir ⇒ Adhesive ⇒ Liner Backing ⇒ Adhesive ⇒ Liner Backing ⇒ Adhesive ⇒ Reservoir ⇒ Liner Backing ⇒ Matrix ⇒ Adhesive ⇒ Liner Backing ⇒ Adhesive ⇒ Matrix ⇒ Liner Clear my choice
Question
Multi-layer drug in adhesive TDDS consists of : Question 16AnswerBacking ⇒ Reservoir ⇒ Adhesive ⇒ Liner Backing ⇒ Adhesive ⇒ Liner Backing ⇒ Adhesive ⇒ Reservoir ⇒ Liner Backing ⇒ Matrix ⇒ Adhesive ⇒ Liner Backing ⇒ Adhesive ⇒ Matrix ⇒ Liner Clear my choice
Solution
The multi-layer drug in adhesive transdermal drug delivery system (TDDS) typically consists of the following layers:
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Backing layer: This is the outermost layer of the system which provides the necessary support and protection to the patch. It is usually made of a flexible and impermeable material.
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Drug reservoir: This layer contains the drug and is usually made of a semi-permeable membrane. The drug is released from this layer in a controlled manner.
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Adhesive layer: This layer helps in adhering the system to the skin. It also provides a pathway for the drug to reach the skin.
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Liner: This is the layer that is in contact with the skin and is removed before the application of the patch.
So, the correct order is: Backing ⇒ Reservoir ⇒ Adhesive ⇒ Liner.
Similar Questions
In ________________ TDDS , the adhesive layer contains the drug.Question 20AnswerSingle layer reservoir Multilayer matrix None of the answers is true Single layer matrixMultilayer Reservoir
A monolithic TDDS contains excess drug to ensure that the drug is released and absorbed at a therapeutic rate through the entire time the patch is meant to be worn before being replaced. True False
Advantages of Matrix TDDS include all of the following, except : Question 11AnswerComplex formulation Excellent skin comfortabilitySimplified patch construction Efficient utilization of sizeLow dose dumping potential
Zero-order release by reservoir (TDDS) is achieved by : Question 17AnswerThe dermis Rate controlling membraneThe startum corneum The liner The adhesive layer
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