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Accumulation of which of the following ions has been shown to cause muscle fatigue? Calcium. Potassium. Sodium. Hydrogen.

Question

Accumulation of which of the following ions has been shown to cause muscle fatigue? Calcium. Potassium. Sodium. Hydrogen.

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Solution

The accumulation of Hydrogen ions (H+) has been shown to cause muscle fatigue. During high-intensity exercise, our bodies produce lactic acid which dissociates into lactate and hydrogen ions. The accumulation of these hydrogen ions is what causes the muscle pH to decrease, leading to muscle fatigue.

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