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The blood-brain barrieruses chemical signals to communicate with the spinal cord.provides support to the brain tissue.tightly regulates the intracellular environment of the CNS.is formed by oligodendrocytes.filters the entry of solutes from the blood into the cerebrospinal fluid.SubmitRequest Answer

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The blood-brain barrieruses chemical signals to communicate with the spinal cord.provides support to the brain tissue.tightly regulates the intracellular environment of the CNS.is formed by oligodendrocytes.filters the entry of solutes from the blood into the cerebrospinal fluid.SubmitRequest Answer

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Solution

The blood-brain barrier (BBB) is a highly selective semipermeable border of endothelial cells that prevents solutes in the circulating blood from non-selectively crossing into the central nervous system's extracellular fluid where neurons reside. The BBB has several important functions:

  1. Tightly regulates the intracellular environment of the CNS: The BBB is crucial in maintaining the chemical composition of the neuronal 'milieu', which is required for proper functioning of neuronal circuits crucial for cognition and other neural functions.

  2. Filters the entry of solutes from the blood into the cerebrospinal fluid: The BBB acts as a filter, allowing only certain substances to pass from the bloodstream into the brain. It allows the passage of water, some gases, and lipid-soluble molecules by passive diffusion, as well as the selective transport of molecules such as glucose and amino acids that are crucial to neural function.

The blood-brain barrier does not use chemical signals to communicate with the spinal cord, nor does it provide support to the brain tissue. It is not formed by oligodendrocytes, but rather by endothelial cells that line the capillaries in the brain. Oligodendrocytes are a type of glial cell in the CNS that form the myelin sheath around nerve fibers, which helps speed up the transmission of electrical signals along the nerves.

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