It refers to transcription silencing of the maternal allele whereas paternal imprinting implies that the paternal allele is inactivateD.Select one:a.Mosaicismb.maternal imprintingc.none of thesed.Y-linkage

Heterozygous single-nucleotide polymorphisms (SNPs) in noncoding regions may be causal for ASE by affecting transcription factor binding affinity or causing differences in chromatin state between alternative alleles with a downstream effect on the rate of transcription. Chromatin modifications also play a key role in allelic imbalance of nongenetic origin (including genomic imprinting and X chromosome inactivation). Interplay can also occur between genetic and epigenetic effects through allele-specific DNA methylation

One _____ is inherited from the father and the other from the mother.Group of answer choicessister chromatidhomologous chromosomechromatin

Describe how disruption of imprinting cancontribute to cancer, using the example of the H19/Igf2 cluster (maximum 200 words). In your answerinclude the following points:Describe the methylationpattern of the paternal allele and how this determines Igf2 expression statusDescribe the methylationpattern of the maternal allele and how this determines Igf2 expression statusDescribe how imprintingat the H19/Igf2 cluster is disrupted in Wilm’s tumourExplain how disruptingimprinting at the H19/Igf2 cluster contributes to cancer.

It is the presence of two or more genetically different cell lines in an individual, all derived from a single zygote.Select one:a.Mosaicismb.Somatic mosaicismc.gonadal mosaicismd.None of the above

Recombinant chromosomes have a mix of paternal and maternal alleles due to