Which of the following enzymes is incorrectly matched with its function?ANSWERPrimase: lays down RNA primersPolymerase I: copies DNA on the leading and lagging strandsHelicase: unwinds DNA helixLigase: forms phosphodiester bonds to seal nicks in the DNA backbone in the lagging strand

To determine which enzyme is incorrectly matched with its function, let's analyze each enzyme and its corresponding function step by step:

1. Primase: lays down RNA primers

   • This is correct. Primase synthesizes short RNA primers that provide a starting point for DNA synthesis.

2. Polymerase I: copies DNA on the leading and lagging strands

   • This is incorrect. DNA Polymerase I is primarily involved in removing RNA primers and replacing them with DNA. DNA Polymerase III is the enzyme that primarily synthesizes DNA on both the leading and lagging strands.

3. Helicase: unwinds DNA helix

   • This is correct. Helicase unwinds the DNA double helix to provide single-stranded templates for replication.

4. Ligase: forms phosphodiester bonds to seal nicks in the DNA backbone in the lagging strand

   • This is correct. DNA Ligase seals nicks in the DNA backbone, particularly on the lagging strand where Okazaki fragments are joined together.

Therefore, the enzyme that is incorrectly matched with its function is Polymerase I: copies DNA on the leading and lagging strands.