Find the odd man out: 10, 25, 45, 54, 60, 75, 8080

The odd one out in this series is 8080.

Here's why:

If you look at the differences between each pair of consecutive numbers, you'll see a pattern:

25 - 10 = 15 45 - 25 = 20 54 - 45 = 9 60 - 54 = 6 75 - 60 = 15 8080 - 75 = 8005

The differences between the numbers are not consistent, but 8080 is significantly larger than the rest and the difference between 8080 and the number before it (75) is much larger than any of the other differences. Therefore, 8080 is the odd one out.