CD8 is a marker of:Select one alternative:An activated macrophageB cellsCytotoxic T cellsHelper T cells

T-cell activation begins when a/n presents an antigen fragment in association with an MHC-II molecule to a helper T cell. Once activated, helper T cells can differentiate into T helper 1 cells which will activate cells and secretes IL-2 to help activate cell-mediated immunity. CD4 helper T cells may also differentiate into T helper cells for B-cell activation, or T helper or T regulatory cells for modulation of the response. An APC may also activate a CD8 T cell when the antigen is complexed with . These CD8 cells are called T cells. Activated CD8 cells will mount a direct attack on target cells through the action of , which punch holes in membranes, and , which then enter through these passageways.

__________ are the most abundant T cells, and their function is to __________.ANSWERT helper cells (CD4+); activate B cells to stimulate the humoral branch of adaptive immunityT cytotoxic cells (CD8+); directly destroy cells that are virus-infectedT helper cells (CD4+); coordinate the adaptive immune responseT cytotoxic cells (CD8+); seek and destroy cancer cells

Le lymphocyte T cytotoxique :AAgit uniquement par contact cellulaire.BPeut agir par le biais de l'ADCC.CNe porte pas les molécules du CMH de classe I.DCoexprime les molécules CD4 et CD8.ENe porte pas la molécule CD3.

__________ T cells are responsible for cell-mediated immunity.Multiple ChoiceHelperMemorySuppressorCytotoxic

Tumours that have efficiently down regulated the expression of MHC molecules can still get cleared by which of these cells Group of answer choices CD4 T cells CD8 T cells NK cells T regulatory cells