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F.A is a 25-year-old female who presented at the KATH psychiatry department with a four-day history of Excessive talking, Poor sleep, Irritability, poor appetite, seeing objects appearing bigger that no one else perceives in clear consciousness History of Presenting complaint:Patient is a user of mental health services for the past 6years. She defaulted medications due to financial constraints on the part of her father.Her mother also indicated that patient and her boyfriend intend to have a child hence she deliberately stopped taking her medications because they were worried that her medications are preventing her from conception.Mental State Examination at Presentation:Appearance: appropriately dressedBehaviour: Irritable and talkative but cooperativeSpeech: spontaneous, coherent, increased rate, tone and volume, pressuredMood: elatedAffect: reactivePerceptions: no auditory hallucinationThinking: stream is pressured, form is circumstantial, paranoid delusions of persecution (believe to be a target of harm by 'Ada Money')Orientation/Attention: well oriented in time, place and person Insight: partial (admits to a behavioral change, says she is not sick, but agreed to take medication)Judgment: goodSocial history:Lives with the boyfriend at BebuMedication History:Tab Quetiapine 300mg note X 1MonthTab Lamotrigine 100mg X 1MonthTab Amitriptyline 25mg note X 1 MonthNB: Amitriptyline was given to help with the patient poor sleep Diagnosis: Bipolar Affective Disorder, current episode mania with psychotic symptomsQuestions:Identify the drug-related problems in the case aboveSuggest appropriate interventions for the problems identified in question (1) above.Discuss three(3) risk factors for the patient's relapse.Review Madam FA's medicationas the PsychiatricPharmacist.Explain why it will not be appropriate to give F.A SodiumValproateWhat counseling measures will you give to this patient?DiscussWill this patient benefit from a long acting antipsychotic?Explain with justificationsState with reasons which of F.A's medications should be avoided if there is uncontrolled hyperglycemia?Mention three(3) symptoms suggestive of mania in F.A condition.State two(2) other mood stabilizers that can be used in F.A"s condition.

Question

F.A is a 25-year-old female who presented at the KATH psychiatry department with a four-day history of Excessive talking, Poor sleep, Irritability, poor appetite, seeing objects appearing bigger that no one else perceives in clear consciousness History of Presenting complaint:Patient is a user of mental health services for the past 6years. She defaulted medications due to financial constraints on the part of her father.Her mother also indicated that patient and her boyfriend intend to have a child hence she deliberately stopped taking her medications because they were worried that her medications are preventing her from conception.Mental State Examination at Presentation:Appearance: appropriately dressedBehaviour: Irritable and talkative but cooperativeSpeech: spontaneous, coherent, increased rate, tone and volume, pressuredMood: elatedAffect: reactivePerceptions: no auditory hallucinationThinking: stream is pressured, form is circumstantial, paranoid delusions of persecution (believe to be a target of harm by 'Ada Money')Orientation/Attention: well oriented in time, place and person Insight: partial (admits to a behavioral change, says she is not sick, but agreed to take medication)Judgment: goodSocial history:Lives with the boyfriend at BebuMedication History:Tab Quetiapine 300mg note X 1MonthTab Lamotrigine 100mg X 1MonthTab Amitriptyline 25mg note X 1 MonthNB: Amitriptyline was given to help with the patient poor sleep Diagnosis: Bipolar Affective Disorder, current episode mania with psychotic symptomsQuestions:Identify the drug-related problems in the case aboveSuggest appropriate interventions for the problems identified in question (1) above.Discuss three(3) risk factors for the patient's relapse.Review Madam FA's medicationas the PsychiatricPharmacist.Explain why it will not be appropriate to give F.A SodiumValproateWhat counseling measures will you give to this patient?DiscussWill this patient benefit from a long acting antipsychotic?Explain with justificationsState with reasons which of F.A's medications should be avoided if there is uncontrolled hyperglycemia?Mention three(3) symptoms suggestive of mania in F.A condition.State two(2) other mood stabilizers that can be used in F.A"s condition.

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Solution

  1. Drug-related problems: The patient has stopped taking her medication due to financial constraints and a desire to conceive. This is a major issue as it can lead to a relapse of her symptoms.

  2. Interventions: The patient should be educated about the importance of adhering to her medication regimen. Financial assistance or cheaper alternatives for her medication should be explored. She should also be advised to consult with her healthcare provider before making any decisions about her medication in relation to conception.

  3. Risk factors for relapse: Stopping medication, financial stress, and the desire to conceive without medical consultation can all contribute to a relapse.

  4. Review of medication: As a Psychiatric Pharmacist, I would recommend that the patient continue with her current medication (Quetiapine, Lamotrigine, Amitriptyline) as they seem to be effective in managing her symptoms. However, the patient's desire to conceive should be taken into account and alternatives should be explored if necessary.

  5. Sodium Valproate: It is not appropriate to give F.A Sodium Valproate as it can cause birth defects if the patient is planning to conceive.

  6. Counseling measures: The patient should be counseled on the importance of medication adherence, the risks of stopping medication, and the need to consult with healthcare providers before making decisions about medication and conception.

  7. Long acting antipsychotic: The patient may benefit from a long acting antipsychotic as it can help with medication adherence. However, this should be carefully considered in light of the patient's desire to conceive.

  8. Medication to avoid in uncontrolled hyperglycemia: Quetiapine should be avoided as it can increase blood sugar levels.

  9. Symptoms of mania: Excessive talking, poor sleep, and irritability are all symptoms of mania.

  10. Other mood stabilizers: Lithium and Carbamazepine are other mood stabilizers that can be used in F.A's condition.

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