Aqueous solution can be incorporated into ointment bases in the followingAscending  order (from less to more water incorporated with ease) .Question 22AnswerWater-soluble ⇒ Water-removable  ⇒  Absorption   ⇒ Oleaginous  Water-soluble ⇒ Absorption ⇒ Water-removable  ⇒ Oleaginous   Oleaginous ⇒ Absorption  ⇒ Water-removable  ⇒ Water-solubleOleaginous ⇒ Water-soluble ⇒ Absorption ⇒ Water-removable  Absorption ⇒ Oleaginous ⇒ Water-soluble ⇒  Water-removable

Matching: Insert the letter of the correct match in front of each term. 2. Suppository 3. Insert 4. Pessary 5. Stick 6. Bougie 7. Palliative 8. Metastable 9. Hygroscopic 10. Adjuvant 11. Auxiliary solvent 12. Elixir 13. Tincture 14. Extraction 15. Disperse System A. A clear sweetened hydroalcoholic solution for oral administration, having stable characteristics that keep water-soluble and alcohol-soluble components in solution B. This kind of material will absorb moisture out of the air C. This is used to augment the solvent action of water or to help stabilize a product D. A condition in which an unstable form appears stable for a period of time; it may slowly transition to a more stable form over time E. This is a two-phase liquid preparation of undissolved or immiscible drug distributed throughout a vehicle for administration F. Alcoholic or hydroalcoholic solution from vegetable materials or chemicals, usually for topical administration, stored in tightly closed containers and protected from light G. Method of preparing solutions by drawing the desired component from the crude drug with a solvent in which the desired extractive is soluble I H. Patient care system that includes physical treatment if available, relief of pain, symptoms, and emotional distress; supports decision-making and quality-of-life improvement when curative treatment is not available I. Older term for a vaginal suppository J. This term is from the French for candle, it refers to slender suppositories for urethral administration K. Solid dosage form in which the API is dispersed in a suitable base and formed into a shape for insertion into a natural body cavity such as the rectum, vagina, or urethra L. Current term for a type of suppository for vaginal or urethral administration M. This is an additive that modifies or enhances the effect of a drug or API N. Dosage form for topical application to specific skin site or area of skin, may include an API, penetration enhancers in a base that melts at body temperature, easy to manufacture and convenient to use

All of the following are true regarding vehicle and product type  used  fortopical application , except :Question 1AnswerWater-soluble bases are non greasy and are easily removedCreams, usually oil-in-water emulsions, spread more easily than ointments and are easier to remove.Ointments  offer greater occlusion and are more effective than pastes at absorbing serous discharge. Oleaginous bases provide greater occlusion and emollient effects than do water-washable bases.Water washable bases are called water removable bases

The two general methods used for the preparation of ointments include which of the following: A. mixing and pressing B. fusion and incorporation C. traction and expulsion D. levigation and trituration

Matching 1. Dermatological 2. Transdermal 3. Ointment 4. Oleaginous 5. Fusion 6. Floccules 7. High Shear Mixing 8. Percutaneous 9. TDDS 10.Plaster 11. Thixotrope 12. Membrane Control 13. Permeability 14. Monolithic A. Physical emulsification of immiscible liquids using a rapidly spinning rotor forcing the liquids together through a stationary piece that has holes, slots or grooves to break up droplets or particles into smaller and smaller particles B. This type of gel must be shaken well to liquefy it so it can be poured C. These have adhesives spread on a backing of paper, fabric, moleskin or plastic D. Trans dermal drug delivery systems are designed for this type of absorption E. A drug-polymer matrix layer is between the backing and the front layers, rate of absorption is controlled by the polymer matrix F. The rate of drug absorption is constant as long as the drug solution in the reservoir is saturated, due to this G. This increases when a chemical enhancer is a component of a TDDS H. This type of product delivers the drug to the general circulation I. For this type of product, skin is the target organ J. Semisolid preparation that may be medicated or not, it is intended for external application K. Components are melted together and stirred, with non-melted components added as the mixture cools until it congeals L. Describes a hydrocarbon base that is generally hydrophobic and feels oily or greasy M. These support the passage of the drug into general circulation using the design features of the system in concert with the skin structure N. Small flakes

Solubilizing the active ingredient using a co-solvent