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The theoretical net ATP yield from a molecule of glucose is ________ ATP molecules.

Question

The theoretical net ATP yield from a molecule of glucose is ________ ATP molecules.

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Solution

The theoretical net ATP yield from a molecule of glucose is 36 to 38 ATP molecules.

Here's a step-by-step breakdown:

  1. Glycolysis: This process happens in the cytoplasm of the cell where one glucose molecule (6 carbons) is broken down into two molecules of pyruvate (3 carbons each). This process produces a net gain of 2 ATP molecules.

  2. Pyruvate Decarboxylation: Each pyruvate is then transported into the mitochondria and converted into Acetyl CoA. This process does not produce ATP.

  3. Krebs Cycle (Citric Acid Cycle): Each Acetyl CoA enters the Krebs cycle. For each glucose molecule, the Krebs cycle turns twice (once for each Acetyl CoA). Each turn of the Krebs cycle produces 1 ATP, so this step produces a net gain of 2 ATP molecules.

  4. Electron Transport Chain (ETC): The NADH and FADH2 produced in the previous steps pass their electrons to the ETC, which uses the energy from these electrons to produce ATP. The ETC produces about 32 to 34 ATP molecules.

So, adding up the ATP from each step, the total theoretical net yield from a molecule of glucose is 36 to 38 ATP molecules. However, it's important to note that in actual cells, the yield is often less due to losses in the process.

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