Type I diabetes is characterised by a total lack of insulin caused by:Question 1Answera.A reduced inflammatory responseb.Less than 50% beta cell destructionc.Acute autoimmune attack on beta cellsd.Helper T cells inhibiting macrophage function within the pancrease.T lymphocytes reacting against beta cells antigens
Question
Type I diabetes is characterised by a total lack of insulin caused by:Question 1Answera.A reduced inflammatory responseb.Less than 50% beta cell destructionc.Acute autoimmune attack on beta cellsd.Helper T cells inhibiting macrophage function within the pancrease.T lymphocytes reacting against beta cells antigens
Solution
Type I diabetes is characterized by a total lack of insulin. This is primarily caused by:
c. Acute autoimmune attack on beta cells
e. T lymphocytes reacting against beta cell antigens
In Type I diabetes, the body's immune system mistakenly attacks and destroys the beta cells in the pancreas that produce insulin. This is an autoimmune response. The destruction is often so thorough that the body can no longer produce any insulin at all, leading to a total lack of insulin. This is why Type I diabetes is also often referred to as insulin-dependent diabetes, as people with this condition must take insulin regularly to survive.
Similar Questions
Which of these statements is correct in relation to Diabetes?Question 51Answera.Type 2 diabetes is characterised by T-cell and macrophage-mediated destruction of β-cells (insulin-producing cells) in the pancreasb.Most individuals with Type 1 diabetes tend to be lean and older than 50.c.Type 2 diabetes is primarily an auto-immune disease.d.Type 2 diabetes is characterised by a defect of post-receptor signalling (insulin resistance).e.Type 2 diabetes may typically be well managed with insulin injections.
Which of the following best describes the pathogenesis of Type 2 DiabetesMellitus?a. It is related to HLA-linked diabetogenic genesb. It is the result of insulin resistance coupled with β cell dysfunctionc. It is caused by immune-related progressive decline in β cell massd. It is the result of AGE-RAGE interactionse. It is the effect of activation of protein Kinase C
What is the cause of Type 1 diabetes mellitus?Multiple ChoiceExcess sugar in the dietA disorder of the immune systemAn effect of agingObesity
Individuals with type 2 diabetes Group of answer choices have pancreases that produce and secrete very little insulin. have an absolute requirement for insulin injections. may often control their disease by diet and exercise. have normal concentrations of glucose in their blood.
What leads to a loss of insulin secretion in a type 1 diabetic?Group of answer choicesReduced sensitivity of the pancreatic beta cells.Decreased activity of the immune system.Death of the pancreatic beta cells.Insulin resistance in the muscle cells.
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