What role does the cAMP-CAP complex play in catabolite regulation?Question 16Answera.It inhibits RNA polymerase from binding to the DNAb.It stimulates the initiation of operon transcriptionc.It acts as a repressor to operon expressiond.It directly metabolizes glucose
Question
What role does the cAMP-CAP complex play in catabolite regulation?Question 16Answera.It inhibits RNA polymerase from binding to the DNAb.It stimulates the initiation of operon transcriptionc.It acts as a repressor to operon expressiond.It directly metabolizes glucose
Solution
The cAMP-CAP complex plays a crucial role in catabolite regulation. It stimulates the initiation of operon transcription. When glucose levels are low, the concentration of cyclic AMP (cAMP) increases. This cAMP binds to the catabolite activator protein (CAP), forming the cAMP-CAP complex. This complex then binds to the promoter region of certain operons (like the lac operon), facilitating the binding of RNA polymerase to the DNA and promoting transcription. Therefore, the correct answer is b. It stimulates the initiation of operon transcription.
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Role of cAMP in cell signalling
Catabolite repression in E. coli primarily demonstrates how:Question 3Answera.The presence of glucose enhances the utilization of lactose.b.Lactose can increase the cAMP levels in the cell.c.Glucose presence inhibits lactose metabolism.d.Glucose and lactose are metabolized simultaneously.
Which of the following best describes the role of catabolite repression in microbial metabolism?Question 18Answera.Increases the production of secondary metabolitesb.Prevents the synthesis of enzymes for secondary carbon sources when a preferred source is availablec.Activates the regulatory genes for enzyme productiond.Promotes the use of less preferred carbon sources
Ask StudybuddyThe activation of the lac operon requires a signaling molecule regulated by what monosaccharide? An increase in the synthesis of tryptophane regulated by Lac z A decrease in cAMP synthesis regulated by an increase in glucose An increase in cAMP regulated by a decrease of glucose A decrease in tryptophane that activates cAMP synthesis An increase in lactose that activates cAMP synthesis
The lac operon system, first described by Jacob and Monod, regulates lactose metabolism in . The is composed of a gene encoding a protein that normally keeps this operon in the position. Within the , the repressor binds to the , blocking transcription of structural genes needed for lactose metabolism. When is added to a cell's environment, it binds the repressor freeing the operator segment of the DNA. is now able to bind to the promoter, transcribing all three structural genes needed for lactose catabolism. When lactose again becomes depleted in the cell, the repressor binds to the operator blocking additional synthesis of enzymes from the .
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