Aneuploidy is a common feature of cancer, and deciphering the mechanisms of chromosomal segregation is of great clinical interest. This segregation depends on the assembly/disassembly of which structures? A) Microfilaments B) Nuclear laminae C) Desmosomes D) Microtubules E) Adherens junctions
Question
Aneuploidy is a common feature of cancer, and deciphering the mechanisms of chromosomal segregation is of great clinical interest. This segregation depends on the assembly/disassembly of which structures?
A) Microfilaments B) Nuclear laminae C) Desmosomes D) Microtubules E) Adherens junctions
Solution
The correct answer is D) Microtubules.
Chromosomal segregation during cell division is a process that heavily relies on the assembly and disassembly of microtubules. These structures form the mitotic spindle, which is responsible for separating the chromosomes into the two daughter cells. Aneuploidy, a condition where a cell has an abnormal number of chromosomes, is often a result of errors in this segregation process. Therefore, understanding the mechanisms of microtubule assembly and disassembly could be crucial in cancer research.
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