advantages of harvesting stem cells in peripheral blood stem cell transplantation
Question
advantages of harvesting stem cells in peripheral blood stem cell transplantation
Solution
Peripheral blood stem cell transplantation (PBSCT) has several advantages:
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Easier Collection Process: The process of collecting stem cells from peripheral blood is less invasive and easier than bone marrow extraction. It involves a simple blood draw, which is less painful and risky for the donor.
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Faster Recovery: After transplantation, patients who receive peripheral blood stem cells tend to recover faster than those who receive bone marrow transplants. This is because peripheral blood stem cells usually start producing new blood cells more quickly.
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Higher Stem Cell Count: Peripheral blood stem cell donation often results in a higher yield of stem cells compared to bone marrow donation. This can be beneficial for the recipient as it may improve the success rate of the transplant.
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Lower Risk of Graft Failure: There is a lower risk of graft failure with peripheral blood stem cells. This means that the transplanted cells are less likely to be rejected by the recipient's body.
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Flexibility: The collection of peripheral blood stem cells can be scheduled more flexibly than bone marrow collection, which can be beneficial for both the donor and the recipient.
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Less Hospitalization: The procedure can often be performed on an outpatient basis, reducing the need for hospitalization.
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Reduced Risk of Anesthesia: Since the procedure does not require general anesthesia, it eliminates the risks associated with it.
However, it's important to note that there are also potential disadvantages to PBSCT, such as a higher risk of chronic graft-versus-host disease (GVHD). Therefore, the decision between PBSCT and bone marrow transplantation should be made on a case-by-case basis, considering the specific circumstances of each patient.
Similar Questions
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Which of the following is a good source of adult stem cells in humans?Bone marrowMuscle cellsBlood cellsNerve cells
Which of the following is an advantage of using embryonic stem cells rather than bone marrow stem cells?Use of bone marrow stem cells has been done many many times and is considered safe, whereas embryonic stem cells still need more research.Embryonic stem cells divide more quickly than bone marrow stem cells.Consent is given by the donor for bone marrow stem cell collection, whereas the use of embryonic stem cells has ethical issues.
Somatic stem cells (also called adult stem cells) exist naturally in the body. They are important for growth, healing, and replacing cells that are lost through daily wear and tear.Potential as therapyStem cells from the blood and bone marrow are routinely used as a treatment for blood-related diseases. However, under natural circumstances somatic stem cells can become only a subset of related cell types. Bone marrow stem cells, for example, differentiate primarily into blood cells. This partial differentiation can be an advantage when you want to produce blood cells; but it is a disadvantage if you're interested in producing an unrelated cell type.Special considerationsMost types of somatic stem cells are present in low abundance and are difficult to isolate and grow in culture. Isolation of some types could cause considerable tissue or organ damage, as in the heart or brain. Somatic stem cells can be transplanted from donor to patient, but without drugs that suppress the immune system, a patient's immune system will recognize transplanted cells as foreign and attack them.Ethical considerationsTherapy involving somatic stem cells is not controversial; however, it is subject to the same ethical considerations that apply to all medical procedures.
The diagram below shows how a new cell that is genetically identical to to the patient is created for therapeutic cloning.The newly created cell is stimulated to divide and a blastocyst will form.Stem cells can be taken from the blastocyst and triggered to differentiate into any cells that are needed.Match the statements below to show whether they are a benefit or a problem with therapeutic cloning.ProblemBenefitPossible AnswersTransplanted tissues are likely to be rejected by the patient.Growing organs from stem cells of an embryonic clone of the patient would reduce the waiting time for organ transplants.It is a much easier process than bone marrow donation.Therapeutic cloning requires the creation and then destruction of an embryo that could develop into a human if allowed.I DON'T KNOWRESETSUBMIT ANSWER
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