A differentiating cell turns on (starts producing) an entire group of genes that are all required in red blood cells (Genes M, N, O P). Which one of the following is the most likely mechanism behind observation? Group of answer choicesGenes M, N, O, P are all regulated by the same cis regulatory elementGenes M, N, O, P are produced from 1 common transcript by alternative splicingGenes M, N, O, P all contain the same protein domainThe DNA for Genes M, N, O, P has just been added to the cell by the process of commitment
Question
A differentiating cell turns on (starts producing) an entire group of genes that are all required in red blood cells (Genes M, N, O P). Which one of the following is the most likely mechanism behind observation? Group of answer choicesGenes M, N, O, P are all regulated by the same cis regulatory elementGenes M, N, O, P are produced from 1 common transcript by alternative splicingGenes M, N, O, P all contain the same protein domainThe DNA for Genes M, N, O, P has just been added to the cell by the process of commitment
Solution
The most likely mechanism behind the observation that a differentiating cell turns on an entire group of genes (M, N, O, P) required in red blood cells is that "Genes M, N, O, P are all regulated by the same cis regulatory element".
Here's why:
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Cis-regulatory elements are regions of non-coding DNA which regulate the transcription of nearby genes. If genes M, N, O, P are all required in red blood cells, it would make sense that they are all regulated by the same cis regulatory element. This would allow for coordinated control of these genes, turning them on or off as needed.
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The other options are less likely. For example, alternative splicing produces different proteins from the same gene, not multiple genes.
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Genes M, N, O, P all containing the same protein domain doesn't necessarily mean they would be produced at the same time.
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The DNA for genes M, N, O, P being added to the cell by the process of commitment doesn't explain how they are all turned on at the same time.
So, the most likely mechanism is that these genes are all regulated by the same cis regulatory element.
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