Which of the following is the most likely phenotypes of a yeast mutant that contains histones that have reduced levels of acetylation?Group of answer choicesThe mutant will require galactose for growth.The mutant will show increased levels of gene expression.The mutant will show decreased levels of gene expression.The mutant will grow rapidly.
Question
Which of the following is the most likely phenotypes of a yeast mutant that contains histones that have reduced levels of acetylation?Group of answer choicesThe mutant will require galactose for growth.The mutant will show increased levels of gene expression.The mutant will show decreased levels of gene expression.The mutant will grow rapidly.
Solution
Histone acetylation is a process that loosens the DNA around histones, allowing for increased gene expression. This is because the acetylation reduces the positive charge on the histones, weakening the interaction between the negatively charged DNA and the histones, and making the DNA more accessible to transcription factors and other proteins involved in gene expression.
Therefore, if a yeast mutant has histones with reduced levels of acetylation, the DNA would be more tightly wound around the histones. This would make the DNA less accessible to the machinery involved in gene expression, leading to decreased levels of gene expression.
So, the most likely phenotype of a yeast mutant that contains histones that have reduced levels of acetylation is: The mutant will show decreased levels of gene expression.
Similar Questions
Which of the following will lead to a decrease in transcription of a gene?A. Increase in histone deacetylases.B. Increase in histone acetyltransferases.C. Decrease in DNA methyltransferases.D. Decrease in CpG methylation of promoter
What is the effect of high levels of histone acetylation on the expression of a gene?Group of answer choicesThis changes the splicing of the geneIt causes the chromatin to condenseThe gene becomes expressed lessThe gene becomes expressed more
Which of the following is most likely to increase expression of a particular gene? Group of answer choicesa mutation in a silencerrecruitment of histone methyltransferasesrecruitment of histone deacetylasescis regulation by a lncRNA
Which of the following processes may result in the silencing or activation of genes?Group of answer choicesHistone AcetylationHistone PhosphorylationHistone MethylationHistone RibosylationNone of the above
Increase in histone deacetylases.B. Increase in histone acetyltransferases.C. Decrease in DNA methyltransferases.D. Decrease in CpG methylation of promoter
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