A father has DMD. He has two daughters, one is normal while the other daughter had DMD. Identify the genotype and phenotype of the mother. Marks = 3
Question
A father has DMD. He has two daughters, one is normal while the other daughter had DMD. Identify the genotype and phenotype of the mother. Marks = 3
Solution
Duchenne Muscular Dystrophy (DMD) is a recessive X-linked genetic disorder. This means a male with the disorder (who has only one X chromosome) will pass the affected X chromosome to all of his daughters but none of his sons.
-
Genotype of the Mother: Since one of the daughters has DMD, the mother must be a carrier of the DMD gene. This means she has one normal X chromosome (X) and one affected X chromosome (X'). So, the genotype of the mother is X'X.
-
Phenotype of the Mother: Even though the mother carries the DMD gene, she does not show symptoms of the disease because it is a recessive disorder. This means the normal X chromosome compensates for the affected one. Therefore, the phenotype of the mother is normal.
Similar Questions
A pedigree diagram shows males and females affected equally, affected children can have unaffected parents, and heterozygotes have a normal phenotype. This is a(n) _____.Group of answer choicesautosomal recessive disorderautosomal dominant disordersex-linked disordermitochondrial disorderNext
A girl with curly hair and dimples but no freckles has a brother with curly hair and freckles but no dimples. She wanted to figure out the possible genotype for herself and her brother related to these characteristics. She did some research and determined which expression of the traits was dominant and which was recessive. She recorded the information in a chart. If the two children have the same biological parents, what is one of the possible genotypes of each child for these three traits based on their descriptions? Sister Brother
Identify the genotypes of...1) a woman with normal blood clotting whose fatherhad hemophilia2) a normal man whose father had hemophilia.
D and E have three children A, B and C. F is A's spouse. D is the grandfather of G. B is the mother of H. F is G's father. Who is the male child of D and E?
What is the resulting genotype of the test cross between male and female parents?
Upgrade your grade with Knowee
Get personalized homework help. Review tough concepts in more detail, or go deeper into your topic by exploring other relevant questions.