Connecting link between glycolysis and TCA cycle is :-Acetyl CoAOAAPyruvic acidCitric acid
Question
Connecting link between glycolysis and TCA cycle is :-Acetyl CoAOAAPyruvic acidCitric acid
Solution
The connecting link between glycolysis and the TCA cycle is Pyruvic acid.
Here's the step by step process:
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Glycolysis: This process occurs in the cytoplasm of the cell where one molecule of glucose (6 carbons) is broken down into two molecules of pyruvic acid (3 carbons each).
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Transition Step: Each pyruvic acid is then converted into Acetyl CoA (2 carbons) in the mitochondria. This step is also known as the link reaction as it links glycolysis and the TCA cycle. During this process, one molecule of carbon dioxide is released.
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TCA Cycle (also known as Krebs Cycle or Citric Acid Cycle): The Acetyl CoA then enters the TCA cycle within the mitochondria. Here, it combines with a 4-carbon molecule to form a 6-carbon molecule (citric acid). Through a series of reactions, the citric acid is converted back to the 4-carbon molecule, ready to accept another Acetyl CoA. During this cycle, two molecules of carbon dioxide are released.
So, the connecting link between glycolysis and the TCA cycle is the conversion of Pyruvic acid to Acetyl CoA.
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