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Which one of the following statements regarding drugs that affect blood glucose level is correct?Group of answer choicesSodium-glucose co-transporter-2 inhibitors decrease the excretion of glucose.Glucagon-like peptide-1 receptor agonists increase glucagon secretion.Biguanides enhance the digestion and absorption of carbohydrates.Sulfonylureas increase insulin release by binding to the ATP-sensitive potassium channel.

Question

Which one of the following statements regarding drugs that affect blood glucose level is correct?Group of answer choicesSodium-glucose co-transporter-2 inhibitors decrease the excretion of glucose.Glucagon-like peptide-1 receptor agonists increase glucagon secretion.Biguanides enhance the digestion and absorption of carbohydrates.Sulfonylureas increase insulin release by binding to the ATP-sensitive potassium channel.

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Solution

The correct statement is: Sulfonylureas increase insulin release by binding to the ATP-sensitive potassium channel.

Here's why:

  1. Sodium-glucose co-transporter-2 inhibitors actually increase the excretion of glucose, not decrease it. They work by preventing the kidneys from reabsorbing glucose back into the blood.

  2. Glucagon-like peptide-1 receptor agonists do not increase glucagon secretion. Instead, they increase insulin secretion and decrease glucagon secretion, which helps to lower blood glucose levels.

  3. Biguanides, such as metformin, do not enhance the digestion and absorption of carbohydrates. They work by decreasing the production of glucose by the liver and increasing the sensitivity of muscle cells to insulin.

  4. Sulfonylureas increase insulin release by binding to the ATP-sensitive potassium channel on the beta cells of the pancreas. This causes the cells to depolarize and release insulin.

This problem has been solved

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Select all that applyWhat are some effects of glucagon?Multiple select question.lowers blood glucose levelsstimulates the conversion of noncarbohydrates (e.g., amino acids) into glucoseraises blood glucose levelsstimulates the liver to break down glycogenstimulates the liver to store glucose as glycogen

Which of the following promotes glucose uptake?Group of answer choicesinsulinadrenalineglucagoncortisol

Which one of the following statements regarding glucagon is TRUE?Question 20Select one:a.Glucagon generally works in opposition to insulin in order to decrease blood glucose levelsb.Glucagon generally works in opposition to insulin so only one hormone (glucagon or insulin) is present in the bloodstream at any one time.c.Glucagon receptors are activated by epinephrine to trigger a cell signalling cascade and stimulate fatty acid release from storaged.Glucagon and insulin are both stimulated by increased amino acids in the bloodstream.e.Both a and d are TRUE.

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