On an mRNA, the triplet grouping of ribonucleotides used by the translation machinery during polypeptide synthesis.Group of answer choicesTATA boxintronexonreading framecodonprimary transcript

Accuracy in the translation of mRNA into the primary structure of a polypeptide depends on:Select one alternative:amino acids being attached to tRNA molecules that contain the correct codon.the anticodon binding to the corresponding codon.small ribosomal subunits binding to specific large ribosomal subunits.ribosomes binding to specific mRNA molecules.

How is mRNA translated?Group of answer choices5' 3' direction3' 5' directionamino-to-carboxyl directioncarboxyl-to-amino directionnone of the above

The nucleotide where RNA polymerase actually begins synthesis of the mRNA.Group of answer choicescodonpromoterA sitestart pointTATA boxintronNext

Which type of RNA brings amino acids to the ribosome during translation?

Translation of mRNA to produce proteins is highly regulated.  For example, one factor that regulates eukaryotic translation is the polyadenylate binding protein (PABP).  PABP upregulates translation by binding the poly-A tail of an mRNA molecule (ie, the 3' end of mRNA consisting of multiple adenosine residues) to help recruit the ribosome.PABP consists of a single polypeptide chain and contains four distinct RNA recognition motifs (RRM's), each of which contains four β-strands and two α-helices.  Mutation experiments revealed that each RRM binds poly-A tails through residues in several β-strands.  Crystallography showed that the two α-helices in each RRM, which consist of amino acids 9-24 and 52-60, respectively, help hold the β-strands in the correct orientation for RNA binding.In addition to binding poly-A tails, PABP can also bind to the eukaryotic initiation factor eIF4G through the α-helices in the RRM regions.  When both eIF4G and mRNA with a poly-A tail are present with PABP, a ternary complex between the three molecules can form.  This complex further enhances translation relative to the PABP-mRNA complex alone.  To better characterize these binding interactions, PABP was electrophoresed in a native gel in the presence of mRNA containing a poly-A tail.  When eIF4G was added, PABP affinity for poly-A tails increased 10-fold.  Additional observations revealed that the affinity of PABP for eIF4G increased 12-fold when mRNA with a poly-A tail was added. Question 55Each of the following amino acid residues is likely to be found in the portion of the RRM that binds eIF4G EXCEPT:A.LeucineB.ArginineC.GlycineD.Serine