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When a mutation occurs by substitution of one base in a DNA sequence, this may result in a:Group of answer choicessilent mutationtranslocation mutationframeshift mutationreciprocal mutation

Question

When a mutation occurs by substitution of one base in a DNA sequence, this may result in a:Group of answer choicessilent mutationtranslocation mutationframeshift mutationreciprocal mutation

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Solution

When a mutation occurs by substitution of one base in a DNA sequence, this may result in a silent mutation.

Here's why:

  1. Silent Mutation: This type of mutation occurs when the change in the DNA sequence does not result in a change in the amino acid sequence of the protein. This is possible due to the degenerate nature of the genetic code, where multiple codons can code for the same amino acid. So, if the substituted base still codes for the same amino acid, the mutation is silent.

  2. Translocation Mutation: This type of mutation involves a piece of one chromosome breaking off and attaching to a different chromosome. This is not caused by a simple base substitution.

  3. Frameshift Mutation: This type of mutation is caused by the insertion or deletion of a base in the DNA sequence, which shifts the reading frame of the genetic code. A base substitution would not cause a frameshift mutation.

  4. Reciprocal Mutation: This is not a standard term in genetics. Perhaps you meant reciprocal translocation, which like translocation mutation, involves the exchange of segments between non-homologous chromosomes and is not caused by a base substitution.

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