In an experiment to determine the distribution coefficient of an acid it was found that the total concentration of the acid in the aqueous layer was 0.341 mol/L and the concentration of the acid in the octan-1-ol layer was 0.112 mol/L. What is the octan-1-ol/water distribution coefficient for this acid?Question 7Answer0.3610.3283.0450.247
Question
In an experiment to determine the distribution coefficient of an acid it was found that the total concentration of the acid in the aqueous layer was 0.341 mol/L and the concentration of the acid in the octan-1-ol layer was 0.112 mol/L. What is the octan-1-ol/water distribution coefficient for this acid?Question 7Answer0.3610.3283.0450.247
Solution
The distribution coefficient (Kd) is defined as the ratio of the concentration of a compound in the organic phase to its concentration in the aqueous phase.
In this case, the concentration of the acid in the octan-1-ol layer is 0.112 mol/L and the concentration of the acid in the aqueous layer is 0.341 mol/L.
So, the distribution coefficient can be calculated as follows:
Kd = [Acid]octan-1-ol / [Acid]aqueous Kd = 0.112 mol/L / 0.341 mol/L Kd = 0.328
So, the octan-1-ol/water distribution coefficient for this acid is 0.328.
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