Which of the following statements is/are correct in relation to rheumatoid arthritis (RA)?W. RA is a chronic inflammatory disease that principally affects joints.X. The concentrations (titres) of Rheumatoid Factor deposited in joints does not influence disease severity.Y. The pathogenesis of joint destruction in RA involves both Type III and Type IV hypersensitivity reactions.Z. Development of RA greatly depends on repetitive impulse loading.Question 50Select one:a.if only W, X and Y are correctb.if only W and Y are correctc.if only X and Z are correctd.if only Z is correcte.if all are correct
Question
Which of the following statements is/are correct in relation to rheumatoid arthritis (RA)?W. RA is a chronic inflammatory disease that principally affects joints.X. The concentrations (titres) of Rheumatoid Factor deposited in joints does not influence disease severity.Y. The pathogenesis of joint destruction in RA involves both Type III and Type IV hypersensitivity reactions.Z. Development of RA greatly depends on repetitive impulse loading.Question 50Select one:a.if only W, X and Y are correctb.if only W and Y are correctc.if only X and Z are correctd.if only Z is correcte.if all are correct
Solution
The correct answer is b. if only W and Y are correct.
Explanation:
W. RA is a chronic inflammatory disease that principally affects joints. - This statement is correct. Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints.
X. The concentrations (titres) of Rheumatoid Factor deposited in joints does not influence disease severity. - This statement is incorrect. Higher levels of Rheumatoid Factor are generally associated with more severe disease and a poorer prognosis.
Y. The pathogenesis of joint destruction in RA involves both Type III and Type IV hypersensitivity reactions. - This statement is correct. The pathogenesis of RA involves both Type III (immune complex-mediated) and Type IV (T-cell mediated) hypersensitivity reactions.
Z. Development of RA greatly depends on repetitive impulse loading. - This statement is incorrect. While physical activity can exacerbate symptoms in some people with RA, it is not a primary cause of the disease. The exact cause of RA is unknown, but it is believed to involve a combination of genetic and environmental factors.
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