What is the function of the sigma factor in RNA synthesis? A. Terminates transcription B. Helps the RNA holoenzyme recognize the promoter C. All of the above D. Catalyzes RNA synthesis
Question
What is the function of the sigma factor in RNA synthesis? A. Terminates transcription B. Helps the RNA holoenzyme recognize the promoter C. All of the above D. Catalyzes RNA synthesis
Solution
The function of the sigma factor in RNA synthesis is B. Helps the RNA holoenzyme recognize the promoter.
Here's a step-by-step explanation:
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The sigma factor is a protein needed only for initiation of RNA synthesis. It is a bacterial transcription initiation factor that enables specific binding of RNA polymerase to gene promoters.
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The specific sigma factor used will recognize the promoters of genes appropriate to the cell's needs at the time.
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Once the first bond is synthesized, the sigma factor is released. This allows the core enzyme to proceed with the elongation phase
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