Bacterial capsules __________.ANSWERallow for cells to live in phagocytic cellscan block fusion of lysosomes with the phagosomeallow for avoidance of phagocytosisrelease toxins that kill phagocytes
Question
Bacterial capsules __________.ANSWERallow for cells to live in phagocytic cellscan block fusion of lysosomes with the phagosomeallow for avoidance of phagocytosisrelease toxins that kill phagocytes
Solution
Bacterial capsules have several functions that contribute to their survival and virulence:
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Allow for cells to live in phagocytic cells: Some bacteria can survive and even multiply within phagocytic cells, which are cells of the immune system that ingest and destroy pathogens. The capsule can protect the bacteria from the destructive enzymes within these cells.
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Can block fusion of lysosomes with the phagosome: When a bacterium is engulfed by a phagocytic cell, it is enclosed in a compartment called a phagosome. Normally, this phagosome would fuse with a lysosome, another compartment that contains enzymes to break down the bacterium. However, some bacteria can prevent this fusion, allowing them to survive within the phagocyte.
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Allow for avoidance of phagocytosis: The capsule can also prevent the bacterium from being engulfed by phagocytic cells in the first place. It can do this by inhibiting the binding of the bacterium to the phagocyte, or by mimicking the host's own cells so the immune system does not recognize it as foreign.
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Release toxins that kill phagocytes: Some bacteria can produce toxins that kill phagocytic cells, further helping them to avoid the immune response. These toxins can be released from the capsule.
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Capsule can help a pathogen evade phagocytosis.
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