Which one of the following statements about carbohydrates is CORRECT? A. Glucose residues in glycogen are joined by β-1,4 glycosidic linkages. B. Glycosyltransferases catalyse the biosynthesis of oligosaccharides by transfer of a monosaccharide from a nucleotide sugar to a carbohydrate acceptor.
Question
Which one of the following statements about carbohydrates is CORRECT? A. Glucose residues in glycogen are joined by β-1,4 glycosidic linkages. B. Glycosyltransferases catalyse the biosynthesis of oligosaccharides by transfer of a monosaccharide from a nucleotide sugar to a carbohydrate acceptor.
Solution
The correct statement about carbohydrates is B. Glycosyltransferases catalyse the biosynthesis of oligosaccharides by transfer of a monosaccharide from a nucleotide sugar to a carbohydrate acceptor.
Here's why:
A. This statement is incorrect. Glucose residues in glycogen are primarily joined by α-1,4 glycosidic linkages, not β-1,4. The α-1,6 glycosidic linkages occur at the branch points in glycogen.
B. This statement is correct. Glycosyltransferases are enzymes that catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The donor is usually a nucleotide sugar (a sugar molecule in which the hydroxyl group has been replaced with a nucleotide), and the acceptor may be a variety of molecules including carbohydrates, lipids, proteins, or nucleic acids. This process is critical for the biosynthesis of oligosaccharides.
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