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Which solvent has the lowest energy of activation for an SN1 reaction?Select answer from the options belowAcetoneHexaneEthanolHMPA

Question

Which solvent has the lowest energy of activation for an SN1 reaction?Select answer from the options belowAcetoneHexaneEthanolHMPA

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Solution

The solvent with the lowest energy of activation for an SN1 reaction is Hexane. This is because SN1 reactions are unimolecular nucleophilic substitution reactions that prefer polar protic solvents, which are able to stabilize the transition state and carbocation intermediate. However, among the options given, Hexane, a non-polar solvent, would have the lowest energy of activation because it does not stabilize the transition state or intermediate as much as polar protic solvents, thus requiring less energy to reach the transition state.

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