n muscle tissue, adrenaline signalling results inGroup of answer choicesDephosphorylation of the bifunctional PFK-2/FBPase-2 enzyme which increases glycolysis.Phosphorylation of glycogen phosphorylase which decreases glycogenolysis.Increased levels of fructose-1,6-bisphosphate production, which allosterically upregulates pyruvate kinase.The R state of phosphofructokinase-1 is not stabilised which decreases glycolysis.
Question
n muscle tissue, adrenaline signalling results inGroup of answer choicesDephosphorylation of the bifunctional PFK-2/FBPase-2 enzyme which increases glycolysis.Phosphorylation of glycogen phosphorylase which decreases glycogenolysis.Increased levels of fructose-1,6-bisphosphate production, which allosterically upregulates pyruvate kinase.The R state of phosphofructokinase-1 is not stabilised which decreases glycolysis.
Solution
In muscle tissue, adrenaline signalling results in phosphorylation of glycogen phosphorylase which increases glycogenolysis.
Here's a step-by-step explanation:
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Adrenaline, also known as epinephrine, is a hormone that is released in response to stress or danger. It prepares the body for a 'fight or flight' response by increasing heart rate, blood pressure, and energy production.
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One of the ways adrenaline increases energy production is by stimulating the breakdown of glycogen, a stored form of glucose, into glucose that can be used for energy. This process is known as glycogenolysis.
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The enzyme that catalyzes this breakdown of glycogen is called glycogen phosphorylase.
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When adrenaline binds to its receptor on muscle cells, it triggers a series of reactions that result in the phosphorylation (activation) of glycogen phosphorylase.
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Once activated, glycogen phosphorylase breaks down glycogen into glucose-1-phosphate, which can then be converted into glucose-6-phosphate and used in glycolysis to produce energy.
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Therefore, in muscle tissue, adrenaline signalling results in the phosphorylation of glycogen phosphorylase, which increases glycogenolysis.
So, the correct answer is "Phosphorylation of glycogen phosphorylase which increases glycogenolysis".
Similar Questions
In the liver, adrenaline signalling results inGroup of answer choicesDephosphorylation of glycogen synthase which decreases glycogenesis.The T state of Phosphofructokinase-1 is stabilised which increases glycolysis.Phosphorylation of the bifunctional PFK-2/FBPase-2 enzyme which increases glycolysis.Phosphorylation of glycogen phosphorylase which increases glycogenolysis.
PFK1 is a key enzyme in the mammalian glycolytic pathway. Discuss the effects of ATP, AMP, PEP and citrate on PFK1 activity and, therefore, on cellular metabolism more broadly (10 marks) Discuss the effects of fructose 2,6 bisphosphate on PFK1 activity and the significance of this regulation (5marks) Why is this step so heavily controlled? (5 marks)
In the liver, insulin signalling up-regulates glycolysis. Which of the following signalling pathways explains that mechanism?Group of answer choicesIt activates protein phosphatase-1 which dephosphorylates glycogen phosphorylase.It results in the activation of cAMP dependent protein kinase A (PKA) which phosphorylates pyruvate kinase.It activates the expression of hexokinase, PFK-1 and pyruvate kinase.It results in an increased expression of phosphoenolpyruvate carboxykinase and glucose-6-phosphatase.
Gluconeogenesis, must bypass irreversiblereactions of glycolysis, except:a. Hexokinaseb. Phosphohexose isomerasec. Pyruvate kinased. Phosphofructokinase
An enzyme used in gluconeogenesis but NOT glycolysis is:Group of answer choicesglucose 6-phosphatasephosphofructokinase-1pyruvate kinasehexokinase
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