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Which of the following statements about rational design is most accurate?1 pointIt requires extra strutural / mechanistic /molecular modelling data but not intense screeningIt requires intensescreening but not extra strutural / mechanistic / molecular modelling dataNone of the aboveIt requires intensescreening and extra strutural / mechanistic / molecular modelling dataIt requires neitherstrutural / mechanistic / molecular modelling data nor intense screening

Question

Which of the following statements about rational design is most accurate?1 pointIt requires extra strutural / mechanistic /molecular modelling data but not intense screeningIt requires intensescreening but not extra strutural / mechanistic / molecular modelling dataNone of the aboveIt requires intensescreening and extra strutural / mechanistic / molecular modelling dataIt requires neitherstrutural / mechanistic / molecular modelling data nor intense screening

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Solution

The most accurate statement about rational design is: "It requires intense screening and extra structural / mechanistic / molecular modelling data". Rational design is a method in drug design that requires both intense screening to identify potential drug candidates, and additional structural, mechanistic, and molecular modelling data to understand how these candidates may interact with their targets. This approach is based on the understanding of the molecular basis of diseases and how drugs affect their target molecules or pathways.

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