The Krebs cycle still operates, even though the concentration of oxaloacetate in the mitochondrial matrix is low. Because:Group of answer choicesAcetyl-CoA is a negative allosteric modulator of the PDH complexthe hydrolysis of a thioester bond is highly favourableThe interconversion of L-malate and oxaloacetate is readily reversibleThe ΔG’0 for the formation of oxaloacetate from L-malate is large and positive

Which statement about reaction shown below is CORRECT?   Group of answer choicesThis reaction is the final step of the Krebs cycle and occurs in the mitochondrial inter membrane space.This dehydrogenation reaction is coupled to the oxidation of NAD+ to NADH.In the forward direction, a hydroxyl undergoes a dehydration reaction to form a ketone.This unfavourable reaction (under standard conditions) is driven in part by the highly exergonic hydrolysis of a thioester in the next step.

A mitochondrial deficiency will result in elevated oxaloacetate:malate ratio.TrueFalse

At the start of the Krebs/Citric Cycle, the Acetyl CoA produced during the Link Reaction interact with which molecule?Group of answer choicesCitric acidOxaloacetateHydrogen ionsGlucosePyruvate

It does NOT occur within the mitochondriaABeta-oxidation of fatty acidsBKrebs cycleCGlycolysisDElectron transport chain

Before entering the Krebs cycle, pyruvate is converted toMultiple ChoiceH2O and CO2.glucose.acetic acid.acetyl CoA.ATP.