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Structural changes in the brain in Alzheimer's disease include which of the following:Group of answer choicesSignificant aluminium deposits in the frontal lobeHypertrophy of the hippocampusDeposition of amyloid plaques and neurofibrillary tanglesDegeneration of the basal ganglia

Question

Structural changes in the brain in Alzheimer's disease include which of the following:Group of answer choicesSignificant aluminium deposits in the frontal lobeHypertrophy of the hippocampusDeposition of amyloid plaques and neurofibrillary tanglesDegeneration of the basal ganglia

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Solution

The structural changes in the brain in Alzheimer's disease include the deposition of amyloid plaques and neurofibrillary tangles. These are the characteristic features of Alzheimer's disease.

Amyloid plaques are sticky buildups which accumulate outside nerve cells, or neurons. Neurofibrillary tangles are twisted fibers that build up inside the neurons. Both of these are considered to be the main structural brain changes that occur in Alzheimer's disease.

The other options mentioned, such as significant aluminium deposits in the frontal lobe, hypertrophy of the hippocampus, and degeneration of the basal ganglia, are not typically associated with Alzheimer's disease.

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