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5’- ACAGTCCTTAAGCAAGATAGGTCTAAGATTGCAG-3’ What would be the m-RNA sequence that is complementary to above sequence?

Question

5’- ACAGTCCTTAAGCAAGATAGGTCTAAGATTGCAG-3’ What would be the m-RNA sequence that is complementary to above sequence?

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Solution

The mRNA sequence that is complementary to the given DNA sequence would be:

5'- UGUCAGGAAUUCGUUCUAUCCAGAUUCUAACGUC -3'

Here's how you get it:

  1. Transcription is the process where a segment of DNA is copied into RNA by the enzyme RNA polymerase.

  2. In this process, the DNA sequence is read from the 3' to the 5' end and the mRNA is synthesized in the 5' to 3' direction.

  3. The RNA molecule is complementary to the DNA strand, meaning that for every adenine (A) in the DNA, there will be an uracil (U) in the RNA. For every cytosine (C), there will be a guanine (G), and vice versa.

  4. Therefore, to get the mRNA sequence, you simply replace all the A's in the DNA sequence with U's, all the T's with A's, all the C's with G's, and all the G's with C's.

  5. So, the DNA sequence 5’- ACAGTCCTTAAGCAAGATAGGTCTAAGATTGCAG-3’ would transcribe to the mRNA sequence 5'- UGUCAGGAAUUCGUUCUAUCCAGAUUCUAACGUC -3'.

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