The specialised tissues and organs involved in metabolic regulation include:Group of answer choicesLiver, skeletal muscle, adipose tissue and brainBrain, kidneys, adipose tissue and red blood cellsBrain, spleen, kidneys and adipose tissueLiver, kidneys, brain and red blood cells

The specialised tissues and organs involved in metabolic regulation include: Liver, skeletal muscle, adipose tissue and brain.

Here's a step-by-step explanation:

1. The liver plays a central role in all metabolic processes in the body. It processes nutrients absorbed by the intestines during digestion into forms that the body can use. It also detoxifies harmful substances.

2. Skeletal muscle is responsible for glucose disposal in the body, and thus plays a significant role in regulating the body's glucose metabolism.

3. Adipose tissue, or fat tissue, stores energy in the form of fat. It also secretes a number of products, including hormones that help to regulate metabolism.

4. The brain, particularly the hypothalamus, plays a crucial role in the regulation of energy balance and metabolism. It integrates signals from the rest of the body to control food intake, energy expenditure, and the storage of energy in fat tissue.

The other options - kidneys, spleen, and red blood cells - also play important roles in the body, but they are not among the main tissues and organs involved in metabolic regulation.