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eicosanoid precursor

Question

eicosanoid precursor

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Solution

The precursor to eicosanoids is arachidonic acid. Here are the steps:

  1. The process begins when a stimulus causes a phospholipase to be activated in a cell membrane.
  2. This phospholipase cleaves a phospholipid molecule to release arachidonic acid.
  3. Once free, arachidonic acid can be converted into eicosanoids through two main pathways: the cyclooxygenase pathway or the lipoxygenase pathway.
  4. In the cyclooxygenase pathway, arachidonic acid is converted into prostaglandins and thromboxanes.
  5. In the lipoxygenase pathway, it is converted into leukotrienes.
  6. These eicosanoids then act as signaling molecules and have various effects on the body, such as inflammation, fever, regulation of blood pressure, and induction of labor.

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