From your understanding of immunopathology and hypersensitivity reactions, which of the following statements is/are correct?Question 25Select one:a.Antibody bound to antigen activates the complement cascade to generate inflammation.b.The cell-mediated immune response underpins Type IV hypersensitivity reactions.c.T-helper cells are involved in both antibody-mediated and cell-mediated immune responses.d.Plasma cells form specific antibodies against antigens.e.All these statements are correct.

All these statements are correct.

a. Antibody bound to antigen activates the complement cascade to generate inflammation: This is true. When an antibody binds to an antigen, it can activate the complement system, a part of the immune system that enhances the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's cell membrane.

b. The cell-mediated immune response underpins Type IV hypersensitivity reactions: This is also true. Type IV hypersensitivity is a cell-mediated immune response. In this type of reaction, the antigen is presented to T cells, which then either become activated and kill the cell presenting the antigen or release cytokines that recruit other cells to the site of the antigen.

c. T-helper cells are involved in both antibody-mediated and cell-mediated immune responses: This is correct. T-helper cells are a type of T cell that play an important role in the immune system, particularly in the adaptive immune system. They help in the maturation of B cells into plasma cells and memory B cells, and they also assist in the activation of cytotoxic T cells and macrophages.

d. Plasma cells form specific antibodies against antigens: This is true. Plasma cells are the cells that produce the antibodies in the body. They are generated in the B cells' germinal centers and are responsible for the body's immune response.

So, all these statements are correct.