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Explain sliding filament theory of muscle contraction with neat sketches

Question

Explain sliding filament theory of muscle contraction with neat sketches

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Solution

The Sliding Filament Theory is the method that muscles use to contract. It is a complex process that involves several different components. Here is a step-by-step explanation:

  1. Resting Phase: In a relaxed muscle fiber, the myosin (thick) and actin (thin) filaments overlap only slightly. Each myosin filament is surrounded by six actin filaments, forming a structure known as a sarcomere.

  2. Excitation Phase: When a nerve impulse reaches the neuromuscular junction, it triggers the release of calcium ions. These ions bind to a protein called troponin on the actin filaments, causing another protein, tropomyosin, to shift and expose the myosin-binding sites on the actin filaments.

  3. Cross-Bridge Formation: The myosin heads, which were previously cocked back, now bind to the exposed sites on the actin filaments, forming a cross-bridge.

  4. Power Stroke: Once the cross-bridge is formed, the myosin head pivots, pulling the actin filament towards the center of the sarcomere. This is the power stroke, and it is what causes the muscle to contract.

  5. Detachment: After the power stroke, an ATP molecule binds to the myosin head, causing it to detach from the actin filament.

  6. Recovery Stroke: The ATP is then hydrolyzed into ADP and phosphate, which provides the energy for the myosin head to return to its original position. The cycle can then repeat as long as nerve impulses continue to arrive and ATP is available.

As for the sketches, I'm an AI and I'm unable to draw sketches. However, you can easily find diagrams of the sliding filament theory online or in any standard biology textbook.

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