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How many ATP molecules are used and produced per molecule of glucose during glycolysis?A. The first half of glycolysis uses 4 ATPs, and the second half of glycolysis produces 2 ATPs.B. The first half of glycolysis produces 4 ATPs, and the second half of glycolysis uses 2 ATPs.C. The first half of glycolysis uses 2 ATPs, and the second half of glycolysis produces 4 ATPs.D. The first half of glycolysis produces 2 ATPs, and the second half of glycolysis uses 4 ATPs.

Question

How many ATP molecules are used and produced per molecule of glucose during glycolysis?A. The first half of glycolysis uses 4 ATPs, and the second half of glycolysis produces 2 ATPs.B. The first half of glycolysis produces 4 ATPs, and the second half of glycolysis uses 2 ATPs.C. The first half of glycolysis uses 2 ATPs, and the second half of glycolysis produces 4 ATPs.D. The first half of glycolysis produces 2 ATPs, and the second half of glycolysis uses 4 ATPs.

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Solution

During glycolysis, the breakdown of glucose, there are two main phases: the energy investment phase and the energy payoff phase. In the energy investment phase, two ATP molecules are used to activate glucose, resulting in the formation of fructose-1,6-bisphosphate. This is the first half of glycolysis.

In the energy payoff phase, fructose-1,6-bisphosphate is broken down into two molecules of glyceraldehyde-3-phosphate. During this process, four ATP molecules are produced through substrate-level phosphorylation. This is the second half of glycolysis.

Therefore, the correct answer is option C: The first half of glycolysis uses 2 ATPs, and the second half of glycolysis produces 4 ATPs.

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