Binding of prokaryotes DNA dependent RNA polymerase to promoter site is inhibited by:Select one:a. Rifampicinb. Isoniazidc. Streptomycind. PuromycinClear my choice
Question
Binding of prokaryotes DNA dependent RNA polymerase to promoter site is inhibited by:Select one:a. Rifampicinb. Isoniazidc. Streptomycind. PuromycinClear my choice
Solution
The binding of prokaryotes DNA dependent RNA polymerase to the promoter site is inhibited by:
a. Rifampicin
Rifampicin is an antibiotic that works by inhibiting the DNA-dependent RNA polymerase of bacteria, preventing it from binding to the promoter site on the DNA and thus stopping RNA synthesis. This effectively halts the production of proteins necessary for the bacteria to grow and reproduce.
b. Isoniazid, c. Streptomycin, and d. Puromycin do not inhibit the binding of prokaryotes DNA dependent RNA polymerase to the promoter site.
Isoniazid is an antibiotic that inhibits the synthesis of mycolic acid, a component of the bacterial cell wall. Streptomycin works by binding to the bacterial ribosome, interfering with protein synthesis. Puromycin also interferes with protein synthesis, but it does so by causing premature chain termination during translation.
So, the correct answer is a. Rifampicin.
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