Once the study population has been defined, the denominator of a risk is affected by which of the following? (You must choose all that apply to receive credit for this question; no partial credit will be awarded.)1 pointloss to follow-upmigration who is at risk of developing the health outcomedeathsbirths
Question
Once the study population has been defined, the denominator of a risk is affected by which of the following? (You must choose all that apply to receive credit for this question; no partial credit will be awarded.)1 pointloss to follow-upmigration who is at risk of developing the health outcomedeathsbirths
Solution
The denominator of a risk in a study population can be affected by several factors. Here are the ones that apply from your list:
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Loss to follow-up: This refers to participants who are no longer participating in the study for various reasons (moving, lack of interest, etc.). This can affect the denominator because it reduces the total number of participants, which can skew the results.
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Migration: This can affect the denominator if participants move in or out of the study area. If people move out, it can reduce the denominator (similar to loss to follow-up). If people move in, it can increase the denominator, but these people may not have the same risk factors as the original population, which can also skew the results.
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Who is at risk of developing the health outcome: This is essentially the definition of the denominator in a risk calculation. The denominator is the total number of people who could potentially experience the health outcome. If this changes (for example, if a new risk factor is discovered), it can affect the denominator.
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Deaths: Deaths can reduce the denominator because they reduce the total number of participants. However, if the death is related to the health outcome being studied, it should be counted in the numerator (the number of people who experienced the health outcome), not removed from the denominator.
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Births: In general, births would not affect the denominator because newborns would not be part of the original study population. However, if the study is longitudinal and lasts many years, the children of the original participants could potentially be included in the study population, which would increase the denominator.
Similar Questions
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