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Which of the following hormones affects the rate of reabsorption of water in the collecting duct of the nephron by regulating the insertion of aquaporins into cell membranes?

Question

Which of the following hormones affects the rate of reabsorption of water in the collecting duct of the nephron by regulating the insertion of aquaporins into cell membranes?

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Solution

The hormone that affects the rate of reabsorption of water in the collecting duct of the nephron by regulating the insertion of aquaporins into cell membranes is Antidiuretic hormone (ADH), also known as vasopressin.

Here are the steps of how it works:

  1. When the body is dehydrated, the hypothalamus in the brain detects this and releases ADH from the posterior pituitary gland.

  2. ADH then travels in the bloodstream to the kidneys.

  3. Once at the kidneys, ADH acts on the cells of the collecting duct.

  4. It increases the permeability of the duct cells to water by causing aquaporins to be inserted into their cell membranes.

  5. This allows more water to be reabsorbed from the urine back into the blood, thus concentrating the urine and reducing urine volume.

  6. As a result, the body retains more water, helping to maintain blood pressure and hydration levels.

  7. When the body is rehydrated, the hypothalamus detects this and reduces the release of ADH. This in turn reduces the reabsorption of water, leading to the production of more dilute urine.

This problem has been solved

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