A 29-year-old man who recently completed a course of antibiotics for nongonococcal urethritis secondary to Chlamydia trachomatis presents with diffuse joint pain. The patient describes the pain as particularly bothersome in his low back and left knee. The patient is otherwise healthy and has no other complaints. Physical examination reveals an afebrile man with normal vital signs. The patient's left knee is markedly swollen, erythematous, and exquisitely tender to palpation. Head and neck examination reveals bilateral redness in the eyes with epiphora. Joint aspiration is performed which reveals a leukocyte count of 11,000/mm3. Synovial fluid analysis also reveals a predominance of polymorphonuclear leukocytes. Which of the following is associated with this patient's condition?Ask StudybuddyGroup of answer choicesInflammation of the synoviumArticular cartilage degradationHLA-B27Chronic hyperuricemia
Question
A 29-year-old man who recently completed a course of antibiotics for nongonococcal urethritis secondary to Chlamydia trachomatis presents with diffuse joint pain. The patient describes the pain as particularly bothersome in his low back and left knee. The patient is otherwise healthy and has no other complaints. Physical examination reveals an afebrile man with normal vital signs. The patient's left knee is markedly swollen, erythematous, and exquisitely tender to palpation. Head and neck examination reveals bilateral redness in the eyes with epiphora. Joint aspiration is performed which reveals a leukocyte count of 11,000/mm3. Synovial fluid analysis also reveals a predominance of polymorphonuclear leukocytes. Which of the following is associated with this patient's condition?Ask StudybuddyGroup of answer choicesInflammation of the synoviumArticular cartilage degradationHLA-B27Chronic hyperuricemia
Solution
The patient's symptoms and history suggest that he is suffering from Reactive Arthritis, a type of arthritis that occurs in response to an infection in another part of the body (in this case, Chlamydia trachomatis). This condition is often associated with the genetic marker HLA-B27. Therefore, the answer is HLA-B27.
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30-year-old man presents to his physician with a rash on his left leg. He reports that the rash started as a bug bite and is spreading. He denies any fever, chills, or malaise. His medical history is significant for type 1 diabetes mellitus, and his only medication is insulin. On examination of the left leg, there is a 4-cm area of erythema, swelling, and warmth with indistinct margins. There is no gross purulence. What antibiotic should this patient receive?Ask StudybuddyGroup of answer choicesOral dicloxacillinIV vancomycinOral cephalexinOral clindamycin
27-year-old woman comes to an outpatient urgent care facility because of 3 days of joint pain. She reports significant pain in her wrists, ankles, and knees. She also has had a low-grade fever, fatigue, and a new skin rash. The patient does not have a headache, throat pain, abdominal pain, dysuria, vaginal discharge, or vision changes. She has otherwise been healthy and she takes no medications. She recently began a new sexual relationship with a male partner. The patient has an intrauterine device and does not use condoms. One month ago, she traveled to Connecticut for a camping trip with her parents. She drinks alcoholic beverages socially; she does not smoke or use illicit drugs. Temperature is 38.3°C (101°F), pulse is 96/min, and blood pressure is 127/80 mm Hg. Examination shows a clear oropharynx and no cervical or axillary lymphadenopathy. The abdomen is nontender and there is no hepatosplenomegaly. Upper extremity examination discloses pain along the tendon sheaths during passive and active movement of the hands. Lower extremity examination shows a total of six well-demarcated pustular lesions. Which of the following is the most likely diagnosis?A. BlastomycosisB. Gonococcal infectionC. Lyme diseaseD. Reactive arthritisE. Secondary syphilisProceed to Next ItemShow Explanation
Which of the Following Microorganisms is the most Common Cause of Urethritis59 of 100ACandida albicansBChlamydia TrachomatisCStreptococcus pyogenesDEscherichia Coli
Select all correct descriptions of chlamydia infection.Multiple select question.Untreated infections often cause pelvic inflammatory disease.Chlamydia can cross the placenta and cause blindness or other serious consequences in a newborn.Women typically have mild symptoms resembling a urinary tract infection.Men typically have burning sensation when urinating.Infection can spread to anus, throat, tonsils, and internal organs.
Which of the following is a disease caused by chronic infection with an especially virulent strain of Chlamydia that leads to deforming edema of the genitals?Multiple choice question.Human monocytic ehrlichiosisHuman granulocytic anaplasmosisLymphogranuloma venereumNongonococcal urethritis
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