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Which statement about the effects of opiates on synaptic transmission is false? Group of answer choicesThey act on receptors that are coupled to G proteins that open potassium channels, close calcium channels, and inhibit adenylyl cyclase.They affect presynaptic autoreceptors and reduce the amount of transmitter released.They cause postsynaptic depolarization by opening potassium channels.They cause less transmitter to be released via axoaxonic inhibition.

Question

Which statement about the effects of opiates on synaptic transmission is false? Group of answer choicesThey act on receptors that are coupled to G proteins that open potassium channels, close calcium channels, and inhibit adenylyl cyclase.They affect presynaptic autoreceptors and reduce the amount of transmitter released.They cause postsynaptic depolarization by opening potassium channels.They cause less transmitter to be released via axoaxonic inhibition.

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Solution

The false statement about the effects of opiates on synaptic transmission is: "They cause postsynaptic depolarization by opening potassium channels."

This statement is incorrect because opiates actually cause hyperpolarization, not depolarization. When opiates bind to their receptors, they activate

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