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Which of the following infectious agents are the most difficult to control with standard autoclaving methods?ANSWEREndospore-forming bacteriaEnveloped virusesPrionsProtozoans

Question

Which of the following infectious agents are the most difficult to control with standard autoclaving methods?ANSWEREndospore-forming bacteriaEnveloped virusesPrionsProtozoans

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Solution

Prions are the most difficult infectious agents to control with standard autoclaving methods. This is because prions are proteinaceous infectious particles that lack nucleic acids, which are the usual targets of heat sterilization methods like autoclaving. Prions are extremely resistant to heat, radiation, and many disinfectant procedures, making them difficult to eliminate.

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