When in comes to the adipocyte, insulin resistance manifests as a decreased activity of the HSL enzyme, resulting in a decrease in fatty acid release into the circulation. True False
Question
When in comes to the adipocyte, insulin resistance manifests as a decreased activity of the HSL enzyme, resulting in a decrease in fatty acid release into the circulation. True False
Solution
True. Insulin resistance in adipocytes does indeed manifest as a decreased activity of the hormone-sensitive lipase (HSL) enzyme. This enzyme is responsible for the breakdown of stored fats (triglycerides) into free fatty acids, which can then be released into the bloodstream. When the activity of this enzyme is reduced, less fatty acids are released into the circulation.
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