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In which stage(s) of cellular respiration is NAD⁺ converted to NADH?Group of answer choicescitric acid cycleoxidative phosphorylationglycolysispyruvate oxidation

Question

In which stage(s) of cellular respiration is NAD⁺ converted to NADH?Group of answer choicescitric acid cycleoxidative phosphorylationglycolysispyruvate oxidation

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Solution

NAD⁺ is converted to NADH in the following stages of cellular respiration:

  1. Glycolysis: During this stage, glucose is broken down into two molecules of pyruvate. This process produces a net gain of two NADH molecules.

  2. Pyruvate Oxidation: In this stage, each pyruvate molecule is converted into Acetyl CoA. During this conversion, one NADH molecule is produced for each pyruvate, resulting in a total of two NADH molecules.

  3. Citric Acid Cycle (also known as Krebs Cycle or TCA Cycle): In this cycle, each Acetyl CoA is further broken down and this process produces three NADH molecules per cycle. Since two cycles occur for each glucose molecule (because there are two Acetyl CoA molecules), a total of six NADH molecules are produced in this stage.

Oxidative phosphorylation does not produce NADH. Instead, it is the stage where NADH is used to produce ATP.

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